Laboratory of Organic and Medicinal Chemistry https://mail.orgsyn.in/ 2026-05-06T17:27:56+00:00 https://mail.orgsyn.in/ https://mail.orgsyn.in/_media/favicon.ico text/html 2022-10-14T08:51:39+00:00 Anonymous (anonymous@undisclosed.example.com) https://mail.orgsyn.in/publications/journals/2004_acie_1149?rev=1665737499&do=diff A description for template iteration and search page engine text/html 2023-10-25T04:27:49+00:00 Anonymous (anonymous@undisclosed.example.com) https://mail.orgsyn.in/publications/journals/2023_arkivoc_119?rev=1698208069&do=diff 2-Deoxy-D-glucose (2-DG) is a non-metabolizable glucose analog that has shown promising pharmacological activities and has been used to study the role of glucose in cancer cells. 2-DG is an inhibitor of glycolysis, a potential Energy Restriction Mimetic agent and inhibits pathogen-associated molecular patterns. Its radioisotope derivatives have applications as tracers. Recently, 2-DG has been used as an anti-COVID-19 drug lowering the need for supplemental oxygen. In this review, different synthetic strategies for preparing 2-DG, including enzymatic synthesis, have been discussed. The understanding of these methods would help in developing therapeutics or diagnostic agents aimed at exploring therapeutic targets related to energy metabolism. text/html 2022-10-14T07:08:59+00:00 Anonymous (anonymous@undisclosed.example.com) https://mail.orgsyn.in/publications/journals/start?rev=1665731339&do=diff Index of Research Articles Published in Journals